Episode 3

(Cilia) Size Matters

On this episode of Beyond the Abstract, Derek and Ellen invite Lindsey Avery Fitzsimons, a PhD student at the University of Maine, to discuss new research in the intersecting worlds of heart valve disease and cell biology. A new paper combining mouse genetics and human genome sequencing data uncovers a new role for primary cilia, which are small 'sensors' on cells, in causing mitral valve prolapse. This exemplary study demonstrates the importance of collaboration between physicians and scientists and how basic science can bring about answers to clinical questions.

You can find Lindsey on Instagram @laf_in_the_lab

Toomer et al. Primary cilia defects causing mitral valve prolapse. Science Translational Medicine, 2019. 11(493). PMID: 31118289.

About the Podcast

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Beyond the Abstract
Science and research for everyone

About your hosts

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Derek Sung

Derek is a 4th year MD/PhD student at the University of Pennsylvania interested in developmental and vascular biology with plans to apply into Obstetrics & Gynecology. He is the founder, co-developer, and co-host of Beyond the Abstract.

In his spare time, he likes to listen to All Star by Smash Mouth on repeat, smile too big for photos, pretend to be a sommelier, and throw epic Halloween parties with his roommate.
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Ellen White

Ellen is a 3rd year MD/PhD student at the University of Pennsylvania interested in microbiome research with the hopes of specializing in GI medicine. She is a co-developer and co-host of Beyond the Abstract. You can find her listening to Work by Rihanna (feat. Drake) on repeat, getting too invested in college basketball games, or shamelessly watching Real Housewives.