Episode 11

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Published on:

3rd May 2020

A (Cytokine) Storm is Brewing

COVID-19 is a devastating disease, and the elderly and those with chronic medical conditions are especially at risk. But why is it that some seemingly healthy people also get so sick that they have to be put on a ventilator? The answer may lie in our immune system. This week on Beyond the Abstract, Ellen and Derek explore a new paper that begins to investigate how differences in our immune response to the coronavirus explain why some people get so sick while others do not. Amazingly, they found a key player that causes immune dysregulation and a drug to stop it. Listen as they talk about the implications of this work as well as perhaps the first signs of quarantine insanity...

Giamarellos-Bourboulis et al. Complex immune dysregulation in COVID-19 patients with severe respiratory failure. Cell Host and Microbe, April 2020. DOI: 10.1016/j.chom.2020.04.009. PMID: 32320677.

The information presented here is not medical advice. Please follow all guidelines from the CDC in regards to social distancing. Consult your physician on any questions regarding your personal health.

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About the Podcast

Beyond the Abstract
Science and research for everyone
Hey science nerds! Welcome to Beyond the Abstract, a science podcast dedicated to discussion of the coolest cutting edge, basic science research papers in a way that just about anyone can understand. We're your hosts, Derek and Ellen, two MD/PhD students at the University of Pennsylvania who are passionate about science communication and bridging the gap between science and medicine.

In each episode, we’ll dive into a paper and talk about the experiments these scientists did, what it means for the future of research, and even potential impacts on human health and medicine. We've invited experts in these fields to help us understand and dissect these complicated but impactful papers.

We can't wait to share all this cool science with you.

Disclaimer: This podcast is for informational purposes only and NOT intended as medical advice. The views and opinions expressed are those of the hosts and guests and do not reflect the University of Pennsylvania.

Business contact: beyondabstractpod@gmail.com

About your hosts

Ellen White

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Ellen is a 3rd year MD/PhD student at the University of Pennsylvania interested in microbiome research with the hopes of specializing in GI medicine. She is a co-developer and co-host of Beyond the Abstract. You can find her listening to Work by Rihanna (feat. Drake) on repeat, getting too invested in college basketball games, or shamelessly watching Real Housewives.

Derek Sung

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Derek is a 3rd year MD/PhD student at the University of Pennsylvania interested in developmental and vascular biology with plans to apply into Obstetrics & Gynecology. He is the founder, co-developer, and co-host of Beyond the Abstract.

In his spare time, he likes to listen to All Star by Smash Mouth on repeat, smile too big for photos, pretend to be a sommelier, and throw epic Halloween parties with his roommate.