Episode 6

The Cancer Conundrum

One in eight women will be diagnosed with invasive breast cancer, but how exactly breast cancer metastasizes and spreads to other organs still isn't clear. E-cadherin is a protein that acts as 'molecular glue' that helps cancer cells stick together, but controversy exists within the cancer field about its exact role in cancer spread. This week on Beyond the Abstract, Derek and Ellen take on a paper that lays to rest the role of E-cadherin in breast cancer metastasis. Listen in as they talk about this important paper that definitively addresses this issue once and for all.

Padmanaban et al. E-cadherin is required for metastasis in multiple models of breast cancer. Nature, 2019. 573(7774):439-444. PMID: 31485072.

About the Podcast

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Beyond the Abstract
Science and research for everyone

About your hosts

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Derek Sung

Derek is a 4th year MD/PhD student at the University of Pennsylvania interested in developmental and vascular biology with plans to apply into Obstetrics & Gynecology. He is the founder, co-developer, and co-host of Beyond the Abstract.

In his spare time, he likes to listen to All Star by Smash Mouth on repeat, smile too big for photos, pretend to be a sommelier, and throw epic Halloween parties with his roommate.
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Ellen White

Ellen is a 3rd year MD/PhD student at the University of Pennsylvania interested in microbiome research with the hopes of specializing in GI medicine. She is a co-developer and co-host of Beyond the Abstract. You can find her listening to Work by Rihanna (feat. Drake) on repeat, getting too invested in college basketball games, or shamelessly watching Real Housewives.